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Updated: Aug 29, 2026

Bile Salt-induced Biofilm Formation in Enteric Pathogens: Techniques for Identification and Quantification
Published on: May 6, 2018
Expression of Vibrio vulnificus capsular polysaccharide inhibits biofilm formation
Lavin A Joseph1, Anita C Wright
1Aquatic Food Products Laboratory, Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA.
Abstract:
Vibrio vulnificus is a human pathogen that produces lethal septicemia in susceptible persons, and the primary virulence factor for this organism is capsular polysaccharide (CPS). The role of the capsule in V. vulnificus biofilms was examined under a variety of conditions, by using either defined CPS mutants or spontaneous CPS expression phase variants derived from multiple strains. CPS expression was shown to inhibit attachment and biofilm formation, which contrasted with other studies describing polysaccharides as integral to biofilms in related species.
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