Related Experiment Videos
Carbofuran-induced acute pancreatitis
Evangelos Rizos1, Evangelos Liberopoulos, Paraskevi Kosta
1Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece.
JOP : Journal of the Pancreas
|January 20, 2004
Summary
Acute pancreatitis is a rare complication of carbamate insecticide poisoning. This case report details a patient who developed pancreatitis and a pseudocyst after ingesting carbofuran, highlighting a previously unreported association.
Area of Science:
- Toxicology
- Gastroenterology
- Clinical Medicine
Background:
- Carbamate insecticides are prevalent in agriculture and home gardening.
- Acute pancreatitis is a known, though infrequent, complication of organophosphate and carbamate intoxication.
Observation:
- A 36-year-old woman presented with cholinergic crisis and acute pancreatitis post-ingestion of carbofuran.
- Imaging revealed pancreatic necrosis and a pseudocyst, with no other apparent predisposing factors for pancreatitis.
Findings:
- This case represents the first reported instance of carbofuran intoxication leading to acute pancreatitis and pseudocyst formation.
- Recovery was achieved with supportive care, with normalization of pseudocholinesterase levels and discharge within one month.
Implications:
- The findings suggest a potential, albeit rare, link between carbofuran exposure and severe pancreatic injury.
- Clinicians should consider carbamate insecticide poisoning in the differential diagnosis of acute pancreatitis, especially in the absence of typical risk factors.