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Updated: Aug 29, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
Published on: April 25, 2025
Refractory rhinosinusitis complicating immunosuppression: application of N-chlorotaurine, a novel endogenous
Michaela Gstöttner1, Markus Nagl, Claus Pototschnig
1Department of Otorhinolaryngology, Leopold-Franzens University of Innsbruck, Innsbruck, Austria.
Abstract:
Severe infections are a frequent complication in immunosuppression following transplantations. In the case reported here, a heart-transplanted patient was treated for refractory rhinosinusitis with a combination of sinus surgery and rinsing with N-chlorotaurine (NCT). The daily rinse was well tolerated and effective. The combination of functional endonasal sinus surgery and topical treatment with NCT appeared effective and well tolerated in antibiotic-resistant sinusitis under immunosuppression.
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