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Updated: Aug 19, 2026

Isolation, Enrichment, and Maintenance of Medulloblastoma Stem Cells
Published on: September 1, 2010
MRI spectrum of medulloblastoma
D P Mueller1, S A Moore, Y Sato
1Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City 52242.
Abstract:
Medulloblastomas have been characterized as solid, homogeneously enhancing, midline masses of the posterior fossa. To evaluate atypical MRI characteristics, we retrospectively reviewed 13 histologically proven medulloblastomas. MRI examinations were correlated with pathologic specimens and operative reports. Atypical features included cyst formation (77%), irregular enhancement (19%), extension through fourth ventricle foramina (15%), and presentation as a cerebellopontine angle mass (8%). We conclude that "atypical" characteristics are common. In the child or young adult, medulloblastomas must be included in the differential diagnosis of any posterior fissa mass.
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