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TRADD interacts with STAT1-alpha and influences interferon-gamma signaling

Duane R Wesemann1, Hongwei Qin, Natalia Kokorina

  • 1Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Nature Immunology
|January 20, 2004
PubMed
Summary

Tumor necrosis factor receptor 1-associated death domain protein (TRADD) forms a complex with signal transducer and activator of transcription 1-alpha (STAT1-alpha) in the nucleus. This interaction regulates interferon-gamma (IFN-gamma) signaling and STAT1-alpha activation.

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