Multifocal stimulation techniques in ophthalmology -- Current knowledge and perspectives

The purpose of this paper is to give a brief overview on the application of multifocal stimulation techniques in ophthalmology. The use of m-sequences as a stimulus sequence allows a high-resolution topographic mapping of sensory function. Outer retinal dysfunction can readily be detected with the multifocal ERG (mfERG). When the inner retinal contribution to the mfERG response is enhanced through adapting the stimulation sequence, the sensitivity of the mfERG to detect retinal dysfunction in glaucoma can be increased. Testing of the entire visual pathway with multifocal cortical evoked visual potentials is also possible and recent studies have focused on reducing interindividual variability. The use of m-sequence stimulation in magnetic encephalography offers new ways to study visual processing without the need to apply electrodes.