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Updated: Aug 29, 2026

Generation of Oligodendrocytes and Oligodendrocyte-Conditioned Medium for Co-Culture Experiments
Published on: February 9, 2020
The oligodendrocyte and its many cellular processes
S E Pfeiffer1, A E Warrington, R Bansal
1Department of Microbiology, University of Connecticut Medical School, Farmington, CT 06030, USA.
Abstract:
The oligodendrocyte (OL) is increasingly providing a model system for probing central issues of cell biology. During development, OL progenitors undergo controlled migration, proliferation and differentiation, secrete and respond to a number of growth factors, and dramatically change their cellular architecture, culminating in the formation of the myelin sheath. This review examines some facets of the OL that make it an especially attractive tool for studying many basic questions in cell biology.
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