Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early pattern formation in the developing Drosophila eye.

B J Thomas1, S L Zipursky

  • 1Department of Biological Chemistry, University of California, Los Angeles, CA 90024, USA.

Trends in Cell Biology
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Germline findings in cancer predisposing genes from a small cohort of chordoma patients.

Journal of cancer research and clinical oncology·2024
Same author

Longitudinal Natural History Study of Children and Adults with Rare Solid Tumors: Initial Results for First 200 Participants.

Cancer research communications·2023
Same author

Temporal control of neuronal wiring.

Seminars in cell & developmental biology·2022
Same author

Localization of sucrose synthase in soybean root nodules.

The New phytologist·2021
Same author

The location of sucrose synthase in root nodules of white clover.

The New phytologist·2021
Same author

Visualizing the distribution of elements within barley leaves by energy dispersive X-ray image maps (EDX maps).

The New phytologist·2021

Complex cellular structures form from simple tissues during development. Studying the Drosophila compound eye reveals how cell differentiation and cell cycle synchronization drive pattern formation, linking proliferation regulation to developmental patterning.

Area of Science:

  • Developmental biology
  • Cell biology
  • Genetics

Background:

  • Complex cellular arrays arise from unpatterned epithelia during development.
  • The Drosophila compound eye serves as a model system for understanding developmental patterning.
  • Early patterning involves coordinated cell differentiation and cell cycle synchronization.

Purpose of the Study:

  • To elucidate the mechanisms regulating the transformation of unpatterned epithelia into complex cellular arrays.
  • To investigate the interplay between cell cycle regulation and pattern formation in the Drosophila compound eye.
  • To identify genes involved in early patterning events and their role in linking proliferation to pattern formation.

Main Methods:

  • Utilizing the Drosophila compound eye as a model organism.

Related Experiment Videos

  • Analyzing genetic factors influencing early developmental patterning.
  • Investigating the coordination of cell differentiation and cell cycle progression.

    • Main Results:

    • Pattern formation in the eye primordium is a highly ordered process.
    • The onset of differentiation is tightly coordinated with cell cycle synchronization.
    • Specific genes have been identified that are crucial for early patterning events.

    Conclusions:

    • The Drosophila compound eye development provides key insights into epithelial morphogenesis.
    • Regulation of cell proliferation is intrinsically linked to pattern formation during development.
    • Identified genes offer a molecular basis for understanding developmental patterning mechanisms.