Related Experiment Video
Updated: Aug 29, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Association of substance abuse and depression among adolescent psychiatric inpatients
Carla Kmett Danielson1, James C Overholser, Zeeshan A Butt
1Case Western University, Cleveland, Ohio, USA. danielso@musc.edu
Objective:
To determine whether depression levels differ among suicide-attempting and non-suicide-attempting adolescent inpatients in relation to their alcohol use.
Method:
Ninety-eight adolescents hospitalized at a midwestern psychiatric hospital completed the Children's Depression Inventory and the Rutgers Alcohol Problem-Drinking Index (RAPI). Based on RAPI scores, adolescents were classified as heavy drinkers (n = 36) or light drinkers and nondrinkers (n = 62).
Results:
Heavy drinkers had significantly more depression than those who were classified as light drinkers or nondrinkers regardless of suicide-attempting status.
Conclusions:
The results demonstrate a positive association between depression levels and problems with alcohol in adolescents, indicating that youth who both suffer from depression and abuse alcohol may be at higher risk for a suicide attempt.
Related Concept Videos
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Depression: Overview
Antidepressant Drugs: MAOIs and Other Agents
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...