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Updated: Aug 1, 2026

Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices
Published on: May 9, 2018
Pathological examination and the reporting of lung cancer specimens
D W Chamberlain1, G F Wenckebach, F Alexander
1Department of Pathology, University Health Network, Toronto, Ontario, Canada. dean.chamberlain@uhn.on.ca
Abstract:
The Lung Cancer Disease Site Group (DSG) of the Cancer Care Ontario Practice Guidelines Initiative first met in January of 1994. Included in the membership were three pathologists who, with the other members of the DSG, felt that a useful contribution to the work of the group would be a recommendation on standardized examination and reporting of lung cancer specimens. This review summarizes the consensus of the Lung Cancer DSG pathologists based on their review of the literature and proposes a standard synoptic report, the Primary Lung Cancer Check-Off Sheet. If generally adopted, this standard would improve the quality of reporting of clinical and pathological stage information. Such high-quality staging information is essential to define patient populations for clinical trials and for outcome analyses.
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