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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources
1Department of Bioinformatics, Medical Faculty, Georg August University Göttingen, Goldschmidtstrasse 1, 37077 Göttingen, Germany. torsten.crass@med.uni-goettingen.de
Bioinformatics (Oxford, England)
|January 22, 2004
Summary
The Helmholtz Network for Bioinformatics (HNB) provides a unified portal to German bioinformatics resources. It features a Guided Solution Finder and automated analysis tasks for regulatory DNA and protein function prediction.
Area of Science:
- Bioinformatics
- Computational Biology
- Genomics
- Proteomics
Background:
- The Helmholtz Network for Bioinformatics (HNB) is a collaborative initiative.
- It integrates resources from eleven German research groups.
- The HNB portal offers a centralized access point for bioinformatics tools and data.
Purpose of the Study:
- To provide a unified web portal for accessing diverse bioinformatics resources.
- To simplify resource discovery for users through an interactive tool.
- To enable automated, complex data analyses via integrated tool cascades.
Main Methods:
- Development of a single web portal for resource aggregation.
- Implementation of a 'Guided Solution Finder' using a questionnaire.
- Creation of automated 'tasks' for complex, multi-server analyses.
Main Results:
- The HNB portal offers convenient access to numerous bioinformatics resources.
- The Guided Solution Finder assists users in identifying appropriate resources.
- Automated cascades streamline analyses of regulatory DNA segments and protein functional properties.
Conclusions:
- The HNB facilitates comprehensive data analysis through integrated resources and automated workflows.
- Users can perform complex analyses without manual data handling.
- The portal enhances accessibility and efficiency in bioinformatics research.
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