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The cornea in exfoliation syndrome
M Stefaniotou1, C Kalogeropoulos, N Razis
1University Eye Clinic of Ioannina, Greece.
Documenta Ophthalmologica. Advances in Ophthalmology
|January 1, 1992
Summary
Exfoliation syndrome (EXS) is linked to a fragile cornea, with lower endothelial cell density and increased thickness. These findings highlight a significant risk factor for cataract surgery in EXS patients.
Area of Science:
- Ophthalmology
- Corneal Science
- Ocular Diseases
Background:
- Exfoliation syndrome (EXS) affects ocular structures.
- Corneal changes in EXS patients require further investigation.
- Understanding EXS-related corneal alterations is crucial for surgical planning.
Purpose of the Study:
- To investigate and compare corneal endothelium and thickness in patients with EXS versus normal individuals.
- To identify potential corneal risk factors associated with EXS.
- To evaluate the impact of EXS on corneal health relevant to cataract surgery.
Main Methods:
- Prospective study of 96 patients over 70 years old.
- Group A: 48 patients with EXS (70 eyes).
- Group B: 48 patients with only senile cataract. Corneal endothelium and central thickness were analyzed.
Main Results:
- Eyes with EXS exhibited significantly lower endothelial cell density (p < 0.05).
- Corneas in the EXS group were significantly thicker (p < 0.05).
- EXS eyes showed reduced hexagonal cells and increased polymegethism compared to controls.
Conclusions:
- Exfoliation syndrome is associated with a fragile cornea.
- Lower endothelial cell density and increased corneal thickness are key findings in EXS.
- These corneal changes represent an additional risk factor for cataract surgery in EXS patients.