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Fever of unknown origin in Turkey
1Yaliboyu cad. Koruluk. Mehpare Basaran sok. No: 15/1, Beylerbeyi, 81210 Istanbul, Turkey. fehmitabak@hotmail.com
Infection
|January 22, 2004
Summary
Fever of unknown origin (FUO) is often caused by infectious diseases, particularly tuberculosis, lymphomas, and adult-onset Still's disease. Diagnostic procedures like laparotomy are crucial for identifying the etiology in challenging FUO cases.
Area of Science:
- Internal Medicine
- Infectious Diseases
- Rheumatology
Background:
- Fever of unknown origin (FUO) etiology varies geographically and socioeconomically.
- Advancements in diagnostics impact the spectrum of FUO-causing diseases.
Purpose of the Study:
- To analyze the etiological spectrum of FUO in a specific patient cohort.
- To identify common causes and diagnostic challenges in FUO.
Main Methods:
- Retrospective review of 117 FUO cases from 1984-2001.
- Analysis of etiological categories and diagnostic procedures.
Main Results:
- Infectious diseases (34%), collagen-vascular diseases (23%), and neoplasms (19%) were the leading causes.
- Tuberculosis (24%), lymphomas (19%), and adult-onset Still's disease (11%) were the most frequent diagnoses.
- Invasive procedures, including laparotomy, aided diagnosis in a significant proportion of cases.
Conclusions:
- Infectious diseases, especially tuberculosis, remain a significant cause of FUO.
- Lymphomas, adult-onset Still's disease, and tuberculosis are key considerations in FUO differential diagnosis.