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Updated: Aug 29, 2026
Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
Intraobserver and interobserver reproducibility in the evaluation of ultrasonic pachymetry measurements of central
S Miglior1, E Albe, M Guareschi
1Department of Ophthalmology, University of Milan Bicocca, Department of Neurosciences and Biomedical Technologies, Via Cadore 48, 20052 Monza, Milan, Italy. stefano.miglior@unimib.it
Purpose:
To assess reproducibility of central corneal thickness (CCT) measurement by means of ultrasonic pachymetry.
Methods:
Fifty one volunteers underwent three sessions of CCT measurements, each consisting of three CCT measurements, performed by each of three different observers. Intra- and interobserver reproducibility was calculated by means of intraclass correlation coefficient (ICC). The expected range of variability between two independent evaluations was calculated using scatter plots of each test-retest difference against their mean. The standard deviation of the mean differences in the test-retest scores was used to describe the differences in the score spread.
Results:
The ICC ranges of the intra- and interobserver evaluations were 0.95-0.97 and 0.89-0.95 respectively; the expected variability was < or = +/-1% and < or = +/- 2% respectively (95% confidence interval).
Conclusions:
The measurement of CCT by means of ultrasonic pachymetry is highly reproducible.