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Related Experiment Videos

[Intestinal tuberculosis presenting as Crohn's disease].

A Suissa1, D Militiano, V Kerner

  • 1Gastroenterology, Dept, Rambam Medical Center, Haifa.

Harefuah
|November 1, 1992
PubMed
Summary

Tuberculosis can affect the gastrointestinal tract, mimicking Crohn's disease. Early diagnosis and treatment with anti-tuberculosis drugs led to a full recovery in a patient presenting with these symptoms.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Pulmonology

Background:

  • Crohn's disease is a chronic inflammatory bowel disease often presenting with abdominal pain, diarrhea, and weight loss.
  • Tuberculosis (TB) is an infectious disease primarily affecting the lungs but can manifest in extrapulmonary sites, including the gastrointestinal tract.
  • Immigrants from high-prevalence TB regions may present with atypical TB manifestations.

Observation:

  • A 24-year-old woman with recent immigration from India presented with symptoms suggestive of inflammatory bowel disease: diarrhea, abdominal pain, and weight loss.
  • Initial suspicion for Crohn's disease was investigated.
  • Diagnostic workup revealed active pulmonary tuberculosis and intestinal tuberculosis affecting both the small and large intestines.

Findings:

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  • The patient was diagnosed with disseminated tuberculosis involving both pulmonary and gastrointestinal systems.
  • Treatment involved a standard anti-tuberculosis regimen: rifampicin (600 mg/day), isoniazid (INH, 300 mg/day), and ethambutol (400 mg/day).

Implications:

  • This case highlights the importance of considering tuberculosis in the differential diagnosis of inflammatory bowel disease, especially in patients from endemic areas.
  • Gastrointestinal tuberculosis can mimic Crohn's disease, necessitating thorough investigation to rule out infectious causes.
  • Prompt diagnosis and appropriate anti-tuberculosis therapy are crucial for successful management and full recovery from intestinal TB.