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[Menetrier's disease associated with ulcerative colitis]
Darko Mirković1, Radoje Doder, Srbislav Ilić
1Vojnomedicinska akademija, Klinika za opstu i vaskularnu hirurgiju, Beograd.
Vojnosanitetski Pregled
|January 24, 2004
Summary
This case study presents a 21-year-old patient with Ménétrier
Area of Science:
- Gastroenterology
- Internal Medicine
- Surgical Pathology
Background:
- Ménétrier's disease is a rare condition characterized by gastric mucosal hypertrophy.
- Ulcerative colitis is a chronic inflammatory bowel disease.
- This case highlights a rare association between these two conditions.
Observation:
- A 21-year-old patient with a history of ulcerative colitis presented with severe anemia and hypoproteinemia.
- Upper endoscopy revealed multiple polyploid changes in the stomach, suspicious for malignancy.
- Conservative treatment for ulcerative colitis exacerbations was ongoing.
Findings:
- Total gastrectomy was performed due to the patient's severe symptoms and concerning endoscopic findings.
- Histopathological examination confirmed Ménétrier's disease as the cause of the gastric changes.
- The patient recovered well post-surgery.
Implications:
- This case underscores the importance of considering Ménétrier's disease in young patients with unexplained gastrointestinal symptoms and inflammatory bowel disease.
- Surgical intervention may be necessary for severe cases refractory to medical management.
- Further research into the pathogenesis and management of associated Ménétrier's disease and ulcerative colitis is warranted.