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Transient cerebellar mutism in the course of acute cerebellitis
Antigone S Papavasiliou1, Charalambos Kotsalis, Stamos Trakadas
1Department of Neurology, Pendeli Children's Hospital, Athens, Greece.
Insights
Transient mutism, a rare symptom in children, can occur with parainflammatory cerebellitis. This case highlights a 3-year-old experiencing severe ataxia and mutism following acute gastroenteritis, emphasizing the need for broader diagnostic considerations.
Area of Science:
- Pediatric Neurology
- Neuroinflammation
Background:
- Transient mutism is a known complication of posterior fossa surgery, cerebellar hemorrhage, or trauma in children.
- Its association with parainflammatory cerebellitis is infrequently documented.
Observation:
- A previously healthy 3-year-old presented with severe cerebellitis post-acute gastroenteritis.
- Key symptoms included significant ataxia and transient mutism.
- MRI showed cerebellar swelling and tonsillar protrusion.
Findings:
- The child experienced a slow and incomplete recovery from cerebellitis.
- Residual neurological deficits included dysphonic and dysarthric speech and motor coordination issues.
- Follow-up imaging revealed vermian and hemispheric cerebellar atrophy.
Implications:
- This case expands the understanding of potential causes of transient mutism in pediatric neurology.
- It underscores the importance of considering infectious or inflammatory triggers for cerebellitis.
- Highlights the long-term neurological sequelae that can follow severe pediatric cerebellitis.
Abstract:
Transient mutism after posterior fossa surgery in children or associated with cerebellar hemorrhage or trauma is a recognized phenomenon. However, its association with parainflammatory cerebellitis has been rarely described. We report on a previously healthy 3-year-old child with severe cerebellitis after acute gastroenteritis of unidentified cause. Severe ataxia and transient mutism were the prevailing clinical features. Magnetic resonance imaging revealed swelling of the cerebellum with protruding cerebellar tonsils at the level of the occipital foramen. Recovery from the acute illness was slow and incomplete. Residual cerebellar dysfunction manifested with dysphonic and dysarthric speech, as well as motor coordination problems and was associated with atrophy of the vermis and cerebellar hemispheres in follow-up studies.
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