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Published on: March 15, 2019
Evidence of exercise-induced arterial hypoxemia in prepubescent trained children
Cédric Nourry1, Claudine Fabre, Frédéric Bart
1UFR STAPS Liévin, Laboratoire d'Analyse Multidisciplinaire des Pratiques et Sportives, Chemin du Marquage, 62800 Liévin, France.
Insights
Exercise-induced arterial hypoxemia (EIAH) can occur in young athletes. This study found EIAH in 7 of 24 trained children, suggesting it
Area of Science:
- Pediatric Exercise Physiology
- Sports Medicine
- Respiratory Physiology
Background:
- Exercise-induced arterial hypoxemia (EIAH) is documented in highly trained adults.
- Prepubescent children have high metabolic demands but limited lung capacity compared to adults.
- The presence of EIAH in young athletes requires investigation.
Purpose of the Study:
- To investigate the occurrence of exercise-induced arterial hypoxemia (EIAH) in trained prepubescent children.
- To identify potential physiological factors associated with EIAH in this age group.
Main Methods:
- Twenty-four trained prepubescent children (age 10.3 ± 0.2 years) underwent pulmonary function tests.
- A graded maximal exercise test on a cycle ergometer was performed.
- EIAH was defined as a ≥4% drop in arterial oxygen saturation (Sao2) from resting levels, measured via pulse oximetry.
Main Results:
- EIAH was observed in 7 out of 24 children.
- Hypoxemic children had significantly lower forced vital capacity (FVC), ventilatory response to exercise (ΔE/ΔCO2), and breathing reserve.
- Tidal volume relative to FVC was higher in hypoxemic children; weekly activity and maximal oxygen uptake were similar between groups.
Conclusions:
- Exercise-induced arterial hypoxemia (EIAH) can occur in trained prepubescent children, even with relatively low maximal oxygen uptake.
- Physiological differences in lung function and breathing mechanics may be associated with EIAH in this population.
- Further research is needed to elucidate the underlying mechanisms of EIAH in young athletes.
Abstract:
Exercise-induced arterial hypoxemia (EIAH) is a recognized phenomenon in highly trained adults. Like adult athletes, prepubescent trained children may develop high-level metabolic demand but with a limited lung capacity in comparison with adults. The purpose of this investigation was to search for evidence of EIAH in prepubescent trained children. Twenty-four prepubescent (age: 10.3 +/- 0.2 y) trained children (10.0 +/- 0.7 h of weekly physical activity) performed pulmonary function tests and a graded maximal exercise test on a cycle ergometer. EIAH was defined as a drop of at least 4% from resting level arterial oxygen saturation (Sao(2)) measured by pulse oximetry. EIAH was observed in seven children. Forced vital capacity (FVC), ventilatory response to exercise (Delta(E)/Deltaco(2)), and breathing reserve at maximal exercise were significantly lower, whereas tidal volume relative to FVC was higher in hypoxemic children than in nonhypoxemic children; weekly physical activity and maximal oxygen uptake were similar. Moreover, positive relationships were found between Sao(2) at maximal exercise and breathing reserve (r = 0.56; p < 0.05) or volume relative to FVC (r = 0.70; p < 0.01). EIAH may occur in prepubescent trained children with a relatively low maximal oxygen uptake (42 mL. min(-1). kg(-1)); however, the mechanisms remain unclear and need to be investigated more accurately.
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