Related Experiment Video
Updated: Jan 13, 2026

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
Pituitary metastasis of follicular thyroid carcinoma
Alexandra Chrisoulidou1, Kalliopi Pazaitou-Panayiotou, Nikolaos Flaris
1Unit of Endocrinology and Endocrine Oncology, Theagenion Anticancer Hospital, 2 A. Simeonidi Street, GR-540 07 Thessaloniki, Greece. alexri@otenet.gr
Objective:
The case of a 60-year-old male patient with follicular thyroid cancer who developed a pituitary mass proved to be a metastasis from thyroid cancer.
Methods:
Assessment with whole-body scan, ultrasound, computed tomography and thyroglobulin measurements.
Results:
Despite surgery and repeated doses of radioiodine, the patient developed diplopia and ptosis of the right eyelid, along with increasing thyroglobulin levels. A pituitary mass was discovered, with no signs of pituitary deficiency. The mass was removed and found to consist of neoplastic cells immunohistochemically positive to thyroglobulin.
Conclusions:
Distant metastases may develop in cases of follicular thyroid carcinoma, even after repeated doses of (131)I. Metastatic follicular thyroid carcinoma to the pituitary is a rare entity.

