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Updated: Aug 29, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Loss of left bundle branch block following biventricular pacing therapy for heart failure: evidence for electrical
José Dizon1, Evelyn Horn, John Neglia
1Department of Medicine, Division of Cardiology, Columbia-Presbyterian Medical Center, Columbia University, New York, USA. JMD11@Columbia.edu
Abstract:
Cardiac resynchronization therapy has been proven to improve symptoms and indices of left ventricular function in patients with heart failure and intraventricular conduction delays. We present a case of a patient with New York Association Class III heart failure and left bundle branch block, who received a biventricular pacemaker in order to achieve cardiac resynchronization. Her symptoms improved markedly, as did left ventricular ejection fraction and dimensions. In addition, her intrinsic QRS duration normalized. This may represent a salutory effect of biventricular pacing on electrical remodeling.
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