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Updated: Aug 29, 2026

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
Published on: March 5, 2022
[Insulin resistance in polycystic ovary syndrome]
Annika K Schröder1, Sascha Tauchert, Olaf Ortmann
1Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Schleswig-Hostein, Campus Lübeck, Lübeck, Deutschland.
Abstract:
With a prevalence of 5-10% the polycystic ovary syndrome (PCOS) is a common disorder of premenopausal women. According to prospective studies abnormal glucose tolerance and diabetes mellitus present in about 10.0% and 35.0% of adult women with PCOS, respectively. PCOS patients have a higher prevalence of cardiovascular risk factors such as hypertension and dyslipidaemia. The rate of spontaneous abortions as well as the risk of developing gestational diabetes is increased in PCOS. Therefore, PCOS is not only a reproductive problem, but a complex endocrine disease with important health implications. The role of glucose metabolism in PCOS, the health consequences and possible interventions are reviewed in this article.
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