Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Confocal microscopy in transplanted human corneas].

Lihui Luo1, Zuguo Liu, Longshan Chen

  • 1Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

Yan Ke Xue Bao = Eye Science
|January 27, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Autologous Immunotherapy on Islet Metabolism and T Cell Immunity in Type 2 Diabetic Rabbits.

Current pharmaceutical biotechnology·2026
Same author

DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway.

Frontiers in pharmacology·2025
Same author

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway.

Frontiers in pharmacology·2025
Same author

Association of Long-Term Oral β-Blocker Use With Cardiac Troponin I and B-Type Natriuretic Peptide in Septic Myocardial Injury: A Retrospective Cohort Study.

Health science reports·2025
Same author

Impact of sodium glucose cotransporter 2 inhibitors on bladder cancer and breast cancer: a pharmacovigilance analysis and Mendelian randomization study.

Expert opinion on drug safety·2025
Same author

[Retrospective analysis of animal-related injuries in 1 266 patients based on the emergency department electronic medical record system].

Zhonghua wei zhong bing ji jiu yi xue·2025

Confocal microscopy allows real-time observation of transplanted corneas after lamellar or penetrating keratoplasty. This technique aids in evaluating surgical outcomes and monitoring corneal health over time.

Area of Science:

  • Ophthalmology
  • Cell Biology
  • Medical Imaging

Context:

  • Human corneal transplantation is a common procedure to restore vision.
  • Assessing the success and long-term health of corneal grafts is crucial.
  • In vivo imaging techniques are needed for detailed morphological evaluation.

Purpose:

  • To evaluate the morphology and structure of transplanted human corneas in real-time.
  • To utilize confocal 2.0 microscopy for in vivo observation of lamellar keratoplasty (LKP) and penetrating keratoplasty (PKP) recipients.

Summary:

  • Confocal microscopy revealed distinct changes in transplanted corneas at different time points post-LKP and PKP.
  • Early post-LKP showed stromal cells, nerves, and reflective dots; nerves disappeared by 1 year.

Related Experiment Videos

  • Post-PKP showed activated keratocytes and normal endothelium initially, with decreased endothelial cell density and persistent striae at 1 year.

    • Impact:

    • Confocal scanning microscopy is a valuable tool for studying corneal graft morphology and construction.
    • This technology can be applied to assess surgical effectiveness, clinical observation, and patient follow-up.
    • Provides detailed insights into the cellular and structural changes within transplanted corneas.