Related Experiment Video
Updated: Jul 14, 2026
16:11
Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Prolonged mechanical support of the left ventricle.
W S Pierce1, J H Donachy, D L Landis
1Department of Surgery, College of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, Pennsylvania 17033, USA.
Circulation
|September 1, 1978
Summary
A novel left ventricular assist pump system effectively supports circulation in calves and patients with cardiac failure. This innovative device aids in unloading the left ventricle, proving crucial for post-cardiac surgery recovery.
Area of Science:
- Cardiovascular Engineering
- Biomedical Devices
- Cardiac Surgery Support
Background:
- Development of a novel left ventricular assist pump system.
- System comprises a modified sac type pump, pneumatic power unit, and synchronizer.
- Pump designed for filling from the left ventricle and discharging into the aorta.
Observation:
- System tested in 12 normal calves for an average of 70 days.
- Evaluated in calves with induced profound left ventricular failure.
- Successfully employed in four patients unable to be weaned from cardiopulmonary bypass post-valve replacement.
Findings:
- Assist pump effectively supports circulation.
- Demonstrates complete unloading of the left ventricle.
- Supported circulation in three of four human patient cases.
Implications:
- Potential for improved outcomes in patients with severe left ventricular dysfunction.
- Offers a viable solution for weaning difficulties after cardiac valve surgery.
- Facilitates recovery of native left ventricular function, enabling device explantation.
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