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Related Experiment Videos

Antimicrobial therapy for gastrointestinal diseases.

Mark G Papich1

  • 1Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA. mark_papich@ncsu.edu

The Veterinary Clinics of North America. Equine Practice
|January 27, 2004
PubMed
Summary

Antibiotic therapy is essential for treating horse infections but carries risks. Common adverse effects include disruption of gut bacteria, leading to colitis and diarrhea in horses.

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Area of Science:

  • Veterinary Medicine
  • Equine Health
  • Pharmacology

Background:

  • Antibiotics remain crucial for managing diverse infections in horses.
  • However, their use necessitates careful consideration of potential adverse effects.

Purpose of the Study:

  • To review the justification for antibiotic therapy in horses for specific conditions.
  • To highlight the common intestinal complications associated with antibiotic administration in equine patients.

Main Methods:

  • Literature review of antibiotic use in horses.
  • Analysis of reported adverse consequences, focusing on gastrointestinal issues.

Main Results:

  • Antibiotic therapy is often justified for treating various equine infections.

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  • Significant risks include disruption of the normal intestinal bacterial flora.
  • Colitis and diarrhea are the most frequent complications observed.

    • Conclusions:

    • While essential, antibiotic use in horses requires a balanced approach, weighing benefits against risks.
    • Monitoring for and managing antibiotic-induced intestinal problems is critical in equine veterinary practice.