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Related Experiment Videos

PMWS: experimental model and co-infections.

G M Allan1, F McNeilly, J Ellis

  • 1Virology Department, Veterinary Research Laboratory, Veterinary Sciences Division, Stoney Road Stormont, DARDNI, Stormont, BT4 SD Belfast, Northern Ireland, UK. gordon.allan@dardni.gov.uk

Veterinary Microbiology
|January 27, 2004
PubMed
Summary
This summary is machine-generated.

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Porcine circovirus type 2 (PCV2) causes economically significant wasting disease in young pigs. Experimental infections confirm PCV2

Area of Science:

  • Veterinary Pathology
  • Swine Disease Research
  • Virology

Background:

  • Porcine circovirus type 2 (PCV2) is identified as the cause of porcine multisystemic wasting syndrome (PMWS).
  • PMWS is an economically significant disease affecting young pigs.
  • Gross and histological lesions associated with PMWS are well-documented.

Purpose of the Study:

  • To review experimental PCV2 infections in different pig models.
  • To consolidate findings from various research groups regarding PCV2 pathogenesis.
  • To draw conclusions about PCV2 infection based on experimental data.

Main Methods:

  • Experimental infection of gnotobiotic (GN) pigs with PCV2.
  • Experimental infection of colostrum-deprived (CD) pigs with PCV2.

Related Experiment Videos

  • Experimental infection of colostrum-fed (CF) pigs with PCV2.

    • Main Results:

    • Detailed review of experimental infection outcomes.
    • Analysis of clinical signs, gross lesions, and histological findings post-PCV2 infection.
    • Comparison of disease progression in GN, CD, and CF pigs.

    Conclusions:

    • Experimental infections provide critical insights into PCV2 pathogenesis.
    • Understanding PCV2 infection dynamics in different pig models aids in disease management.
    • This review synthesizes current knowledge on PCV2-induced disease.