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Juvenile colloid milium: clinical, histological and ultrastructural features
S E Handfield-Jones1, D J Atherton, M M Black
1St. John's Dermatology Centre, St. Thomas' Hospital, London, England.
Journal of Cutaneous Pathology
|October 1, 1992
Abstract:
We report the clinical, histological and ultrastructural features of juvenile colloid milium affecting a brother and sister. In this rare condition, translucent papules develop on sun-exposed areas of skin, with onset in childhood. Histologically and ultrastructurally, the papules consist of amyloid-like material derived from epidermal keratonocytes. A review of the literature suggests a possible genetic abnormality that leads to sun-induced degeneration of keratinocytes.