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Updated: Aug 29, 2026

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
Published on: November 27, 2019
[Acute Liver Failure in patient with liver amyloidosis associated to multiple myeloma]
Marcela Berríos1, Rodolfo Armas-Merino, Carmen Franco
1Servicios de Medicina y Anatomía Patológica, Hospital San Juan de Dios, Santiago, Chile. marceberrios@hotmail.com
Abstract:
We report a 67 years old woman admitted to the hospital for the study of a cholestatic jaundice and massive hepatomegaly. On admission, the patient did not have liver failure. During hospital stay, the patient experienced a progressive deterioration of liver function and a monoclonal gammopathy was detected. An IgG Kappa myeloma-was diagnosed. A fine needle liver biopsy disclosed the presence of amyloid. The patient developed acute liver failure and died three weeks after admission.
