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Ze-Guang Han1, Guo-Ping Zhao, Zhu Chen

  • 1Chinese National Human Genome Center at Shanghai, 250 Bi Bo Road, Zhanjiang High-Tech Park, Pudong, Shanghai 201203, China.

Comptes Rendus Biologies
|January 28, 2004
PubMed

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Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...