Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Sneddon-Wilkinson disease. Four cases report].

F Launay¹, B Albès, P Bayle

¹Service de dermatologie, CHU Purpan, Toulouse, France.

La Revue De Medecine Interne

|January 28, 2004

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Toxicity of polycaprolactone nanoplastics, pristine or weathered in environmental conditions, to human intestinal epithelial cells, in vitro.

NanoImpact·2026

Same author

Optimization of ciliary body cyclophotocoagulation settings: a randomized and controlled pilot study.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2025

Same author

Magneto-mechanical treatment of human glioblastoma cells with engineered iron oxide powder microparticles for triggering apoptosis.

Nanoscale advances·2022

Same author

Skin manifestations of hypereosinophilic syndrome are polymorphous and difficult to treat: A retrospective cohort study.

Annales de dermatologie et de venereologie·2022

Same author

Efficacy of dupilumab in eosinophilic dermatosis of haematologic malignancy (EDHM) needs to be confirmed.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021

Same author

Aggressive locoregional behavior of cutaneous squamous cell carcinoma during ruxolitinib use.

Annales de dermatologie et de venereologie·2021

Subcorneal pustular dermatosis (SPD) is a rare neutrophilic dermatitis. Dapsone is effective, but some patients may require etretinate, and SPD is often linked to IgA monoclonal gammopathy.

Area of Science:

Dermatology
Immunodermatology
Rheumatology

Background:

Subcorneal pustular dermatosis (SPD), also known as Sneddon-Wilkinson disease, is a rare chronic pustular eruption.
This condition is classified within the spectrum of neutrophilic dermatoses.
Its nosological classification remains debated, particularly its relationship with IgA pemphigus.

Observation:

Four cases of SPD are presented, detailing clinical and histological findings.
Immunofluorescence studies were negative in all reported cases.
Associated conditions included IgA monoclonal gammopathy in one patient and seronegative polyarthritis in another.

Findings:

Three out of four patients responded well to dapsone treatment.
One patient initially improved with dapsone but later became resistant, showing a dramatic response to etretinate.

Related Experiment Videos

The association with IgA monoclonal gammopathy is noted, a feature shared with IgA pemphigus.

Implications:

SPD is a chronic condition requiring long-term management.
Treatment strategies may include dapsone, with etretinate as a potential alternative for refractory cases.
Understanding the relationship between SPD and IgA pemphigus is crucial for accurate diagnosis and management.