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Detection of True IgE-expressing Mouse B Lineage Cells
Published on: December 1, 2014
Mac1 positive cells are required for enhancement of splenocytes proliferation caused by bisphenol a
Masao Goto1, Hiroshi Ono, Yuko Takano-Ishikawa
1National Food Research Institute, Kannondai, Ibaraki, Japan. masaogot@nfri.affrc.go.jp
Bioscience, Biotechnology, and Biochemistry
|January 28, 2004
Abstract:
We examined the effects of bisphenol A (BPA) on immune cells and it was shown that BPA upregulated the proliferation of murine splenocytes stimulated with Concanavalin A (ConA). The upregulating effects of BPA were removed with depleting Mac1+ cells from the splenocytes. This study provides evidence for the first time that Mac1+ cells were required for enhancement of splenocytes proliferation caused by bisphenol A.
