[Bone involvement with osteolytic predominance in systemic mastocytosis. A clinical case]

Systemic mast cell disease is a rare condition, in which the frequent involvement of bones is likely to raise diagnostic problems. There are other concomitant visceral involvement as a rule. The skin lesions, if present and recognized, are suggestive. The positive diagnosis of bone lesions can be ensured by biopsy. On the basis of one clinical case, we specify the clinical and radiological appearance of systemic mast cell disease.