Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Acute posterior multifocal epitheliopathy: case report].

Piotr Fryczkowski1, Maria Kmera-Muszyńska, Marcin Grzegorz Prost

  • 1Katedry i Kliniki Okulistycznej II Wydziału Akademii Medycznej w Warszawie. pfryczkowski@wp.pl

Klinika Oczna
|January 30, 2004
PubMed
Summary

This case study highlights an unusual presentation of acute posterior multifocal placoid epitheliopathy (APMPPE) in a diabetic patient. The findings suggest diabetic vascular damage may influence APMPPE duration and recurrence.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Local chemotherapy with conjunctival bevacizumab injections in case of lymphoma tumor.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology·2025
Same author

Efficacy and Safety of Ranibizumab Biosimilar QL1205 in Neovascular Age-Related Macular Degeneration: A Phase III Randomized Trial.

Ophthalmology. Retina·2024
Same author

[Bilateral exudative retinal detachment as the first sign of breast cancer--case report].

Klinika oczna·2016
Same author

X-linked retinoschisis--clinical manifestation, genetic and electrophysiological analysis of three generations with p.Arg197Cys mutation of RS1 gene.

Klinika oczna·2015
Same author

[Scleral necrosis after scleral buckling surgery of the patient with pyoderma gangrenosum].

Klinika oczna·2009
Same author

[Is Helicohacter pylori infection associated with CRS occurrence?].

Klinika oczna·2008

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Vascular Biology

Background:

  • Acute posterior multifocal placoid epitheliopathy (APMPPE) is an inflammatory condition affecting the retina and choroid.
  • The etiology and pathogenesis of APMPPE remain incompletely understood, with ongoing debate regarding the primary site of vascular involvement.

Observation:

  • A 59-year-old male with diabetes presented with blurred vision and was diagnosed with APMPPE.
  • Funduscopic examination revealed characteristic placoid lesions alongside signs of non-proliferative diabetic retinopathy and peripheral drusen.
  • An 8-month observational period included serial ophthalmologic examinations and multimodal imaging (FFA, ICG, USG).

Findings:

  • The study supports the hypothesis that APMPPE originates from the choriocapillaris.

Related Experiment Videos

  • The authors propose a correlation between the duration and recurrence of APMPPE and the integrity of the patient's blood vessels.
  • Diabetic microvascular damage in the retina and choroid is suggested as a potential explanation for the prolonged lesions observed in this patient.

    • Implications:

    • This case underscores the potential impact of systemic conditions like diabetes on the clinical course of APMPPE.
    • Understanding the interplay between diabetic vasculopathy and APMPPE may refine diagnostic and therapeutic approaches.
    • Further research into the vascular mechanisms underlying APMPPE is warranted, particularly in patients with comorbid conditions.