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Updated: Aug 29, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Hormonal therapy options for patients with a rising prostate-specific antigen level after primary treatment for
1University of Michigan Medical Center, Ann Arbor, Michigan 48109-0640, USA. bhellers@umich.edu
Abstract:
At this time, many treatment options exist for primary androgen-deprivation therapy. "Standard" options with long-term results on outcome include orchiectomy, monotherapy with a luteinizing hormone-releasing hormone (LHRH) agonist, and combined androgen blockade using an LHRH agonist and antiandrogen. All treatments are associated with some morbidity related to the reduction of circulating testosterone. For this reason, "alternative" regimens are under active study to determine whether equal outcomes can be achieved with lesser toxicity.
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