Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glycemic status in hyperthyroid subjects.

D T Paul1, F H Mollah, M K Alam

  • 1Department of Biochemistry, Jahurul Islam Medical College, Bagitpur, Kishoregonj.

Mymensingh Medical Journal : MMJ
|January 30, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Potassium Imbalance in Patients with Hypertension and Acute Haemorrhagic Stroke in a Tertiary Level Hospital of Bangladesh.

Mymensingh medical journal : MMJ·2026
Same author

Corrigendum to "Unveiling the role of sintering temperatures in the physical properties of Cu-Mg ferrite nanoparticles for photocatalytic application".

Heliyon·2025
Same author

Knowledge, Attitude and Practice about Hepatitis C Virus Infection among the Health Care Workers in a Tertiary Care Hospital of Bangladesh.

Mymensingh medical journal : MMJ·2025
Same author

Comparison of Vitamin D Deficiency among Obese and Normal Children of Bangladesh.

Mymensingh medical journal : MMJ·2025
Same author

The diagnostic utility of the captopril challenge test for primary aldosteronism in a Bangladeshi population: a prospective study.

Pathology·2025
Same author

Development and evaluation of an early childhood caries prediction model: a deep learning-based hybrid statistical modelling approach.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2025
Same journal

Non-secretory Multiple Myeloma: A Challenge to Diagnose.

Mymensingh medical journal : MMJ·2026
Same journal

Scrotal Cystocele with Right Inguinoscrotal Hernia: A Rare Case Report.

Mymensingh medical journal : MMJ·2026
Same journal

Treatment of Base of Condyle Fracture Using Minimal Access Surgery: Infinitesimal Peri-Angular Pterygomasseteric Transsectioning Approach (IPPTA): A Case Report.

Mymensingh medical journal : MMJ·2026
Same journal

BATH-PLUG Technique in Case of Endoscopic Management of Cerebrospinal Fluid Rhinorrhea.

Mymensingh medical journal : MMJ·2026
Same journal

A Six Year Old Boy with Lepromatous Leprosy: A Case Report Revealing an Unsolved Mystery.

Mymensingh medical journal : MMJ·2026
Same journal

The Correlation between Exposure to Screen Time and Severity of Autism Spectrum Disorder in Children in Bangladesh: A Case-Control Study.

Mymensingh medical journal : MMJ·2026
See all related articles

Thyrotoxicosis, including Graves' disease and toxic multinodular goiter, frequently causes glucose intolerance. This study found a high incidence of impaired glucose tolerance and diabetes mellitus in thyrotoxic patients.

Area of Science:

  • Endocrinology
  • Metabolic Disorders
  • Thyroid Disease

Background:

  • Thyrotoxicosis is a condition characterized by excessive thyroid hormone production.
  • Hyperthyroidism encompasses Graves' disease and toxic multinodular goiter (TMNG).
  • Glucose metabolism can be affected by thyroid dysfunction.

Purpose of the Study:

  • To investigate the prevalence of glucose intolerance in newly diagnosed hyperthyroid patients.
  • To compare the incidence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in Graves' disease versus TMNG.
  • To explore the relationship between thyroid hormone levels and glucose metabolism.

Main Methods:

  • Observational case-control study.
  • Included 65 newly diagnosed hyperthyroid patients (45 Graves' disease, 20 TMNG) and 30 healthy controls.

Related Experiment Videos

  • Diagnoses confirmed by clinical evaluation, FT4, TSH, and Radioactive Iodine Uptake (RAIU) tests.

    • Main Results:

    • 72.3% of thyrotoxic patients exhibited glucose intolerance, significantly higher than European populations.
    • Diabetes mellitus was observed in 11% of Graves' disease patients and 5% of TMNG patients.
    • Impaired glucose tolerance was more prevalent in TMNG (85%) compared to Graves' disease (54%).
    • A positive correlation was found between plasma glucose and FT4 in Graves' disease.

    Conclusions:

    • Glucose intolerance is a common comorbidity in thyrotoxicosis.
    • The pattern of glucose metabolism abnormalities differs between Graves' disease and TMNG.
    • Elevated FT4 levels are associated with higher plasma glucose in Graves' disease.