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Updated: Aug 29, 2026

Photothrombosis-induced Focal Ischemia as a Model of Spinal Cord Injury in Mice
Published on: July 16, 2015
Anterior spinal cord infarction owing to possible fibrocartilaginous embolism
Ashok Raghavan1, Ella Onikul, Monique M Ryan
1Department of Medical Imaging, The Children's Hospital at Westmead, 2145, Sydney, Australia.
Abstract:
Anterior spinal artery syndrome is characterised by acute flaccid quadriparesis or paraparesis, disturbance of pain and temperature sensation, and loss of sphincter control. Fibrocartilaginous embolism is a rarely recognised, but important cause of spinal cord infarction. Fibrocartilaginous embolisation usually occurs after minor trauma without major bony lesions, typically with an intervening symptom-free interval and progressive 'stroke-in-evolution' course. There is evidence that the embolus originates from the intervertebral disc, but the mechanism whereby disc fragments enter the spinal vessels is not well understood. We describe the evolution of MRI findings in a case of anterior spinal artery territory infarction thought to be secondary to fibrocartilaginous embolism.
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