Related Experiment Video
Updated: Aug 29, 2026

A Preterm Rat Model for Pain Studies
Published on: February 9, 2024
[Prevention and pain management in term and preterm infants]
Shaul Dollberg1, Orit Stolik-Dollberg
1Department of Neonatology, Tel Aviv Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Israel.
Insights
Neonatal pain management is crucial, as inadequate analgesia during painful procedures can lead to lifelong adverse effects. Implementing pharmacological and non-pharmacological strategies, including for neonatal circumcision, is essential for infant well-being.
Area of Science:
- Neonatalogy
- Pediatric Pain Management
- Medical Ethics
Context:
- 6-10% of infants in neonatal intensive care units (NICUs) experience pain.
- Repetitive painful procedures without adequate analgesia can cause long-term adverse consequences.
- Neonatal circumcision is a common procedure often performed without sufficient pain relief.
Purpose:
- To highlight the adverse effects of inadequate pain management in neonates.
- To discuss pharmacological and non-pharmacological pain management strategies.
- To advocate for the routine use of analgesia during neonatal circumcision.
Summary:
- Pain in the neonatal period affects a significant percentage of infants requiring NICU care.
- Opioid and non-opioid medications, alongside sensory environment modifications, are key to effective pain management.
- Current practices often neglect analgesia for neonatal circumcision, which is considered unethical by major pediatric associations.
Impact:
- Improved pain management can mitigate long-term negative health outcomes for neonates.
- Implementing recommended analgesia strategies can enhance the quality of care in NICUs.
- Promoting ethical pain management for procedures like circumcision is vital for infant welfare.
Abstract:
Pain in the neonatal period is frequently experienced by 6-10% of newly born infants, preterm and term, who require neonatal intensive care. Repetitive painful procedures without adequate analgesia provided by the medical staff may bear long-term or even life-long adverse consequences. The use of pharmacological and non-pharmacological modalities in the management of pain may change this undesirable situation. The use of opioid analgesia for very painful procedures and the use of non-opioid medications in combination with opioids are essential. A change in the sensory environment of the sick infant is an important additional analgesic effect. In addition to pain management in the neonatal intensive care units, neonatal circumcision is the most frequent surgical procedure performed in males, and is frequently conducted without appropriate analgesia. The simple available methods of analgesia for neonatal circumcision are discussed and should be employed in order to avoid painful circumcision. Many pediatric medical associations in the developed world consider failure to provide proper routine analgesia for neonatal circumcision to be an unethical and sub-optimal medical practice.
Related Concept Videos
Preventive Healthcare Services
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Peripheral Artery Disease V: Postoperative Nursing Management
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
Analgesia and Pain Management
Pulmonary Embolism III: Nursing Management
