Remission of collapsing focal segmental glomerulosclerosis following chemotherapy for myeloma
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Published on: October 17, 2025
Sapna Shah1, Jamie Cavenagh, Michael Sheaf
1Department of Renal Medicine, Barts and the London NHS Trust, London, UK.
Abstract:
Collapsing focal segmental glomerulosclerosis can be idiopathic but has been associated with human immunodeficiency virus infection as well as lymphoproliferative, myeloproliferative, and autoimmune disorders. It has a more rapid progression to end-stage renal failure. Treatment of this condition is poorly defined with no clear evidence of response to any treatment regimens. We report a case of collapsing focal segmental glomerulosclerosis in association with multiple myeloma that underwent partial remission following treatment for the underlying disease.