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Hemostasis in endoscopic sinus surgery using a specific gelatin-thrombin based agent (FloSeal)
Ariane Baumann1, Marco Caversaccio
1Department of ENT, Head and Neck Surgery, University Hospital, Inselspital, Berne, Switzerland.
Rhinology
|January 31, 2004
Summary
FloSeal, a novel hemostatic sealant, offers a safe and effective alternative to nasal packing for sinus surgery. It provides rapid hemostasis with improved patient comfort and satisfaction.
Area of Science:
- Otolaryngology
- Surgical Innovation
- Biomaterials
Background:
- Nasal packing is standard after endoscopic sinus surgery but can cause discomfort.
- A new hemostatic sealant offers a potential alternative for improved patient experience.
Purpose of the Study:
- To evaluate the safety and efficacy of FloSeal as an alternative to nasal packing.
- To compare FloSeal with Merocel packing in functional endoscopic sinus surgery.
Main Methods:
- Prospective clinical study involving 100 patients undergoing bilateral endoscopic anterior ethmoidectomy.
- 50 patients received 2 ml of FloSeal post-surgery.
- 50 patients received traditional Merocel packing for comparison.
Main Results:
- Intraoperative hemostasis was rapid and comparable between FloSeal and Merocel groups.
- FloSeal demonstrated significantly higher patient comfort, particularly in postoperative nasal breathing.
- No significant difference in complications like stenosis or synechia was observed.
- One case of delayed bleeding required repacking; no systemic side effects were reported.
Conclusions:
- FloSeal is a safe and effective hemostatic agent for endoscopic sinus surgery.
- It offers superior patient comfort and satisfaction compared to traditional nasal packing.
- Its ease and speed of application make it a valuable alternative.