Endophthalmitis caused by Acinetobacter calcoaceticus. A profile

Area of Science:

• Ophthalmology
• Infectious Diseases
• Microbiology

Background:

• Endophthalmitis is a severe intraocular inflammation.
• Acinetobacter calcoaceticus is an opportunistic pathogen.
• Understanding its clinical profile is crucial for effective management.

Purpose of the Study:

• To describe the clinical and microbiological characteristics of endophthalmitis caused by Acinetobacter calcoaceticus.
• To evaluate treatment outcomes and identify optimal therapeutic strategies.

Main Methods:

• Retrospective case series analysis of 20 patients with Acinetobacter calcoaceticus endophthalmitis.
• Evaluation of etiological factors (postoperative, posttraumatic, endogenous, bleb-related).
• Assessment of microbiological sample positivity (aqueous and vitreous), ocular sterilization, anatomical results, and visual acuity recovery.

Main Results:

• Acinetobacter calcoaceticus endophthalmitis presented in various forms, including postoperative, posttraumatic, endogenous, and bleb-related.
• Endogenous cases showed chronicity and lacked obvious predisposing factors.
• Ocular sterilization was achieved in most cases; visual recovery was modest.
• Vitreous samples had higher smear and culture positivity than aqueous samples.
• High sensitivity to ciprofloxacin (88.9%) was observed.

Conclusions:

• Visual outcomes in Acinetobacter calcoaceticus endophthalmitis are generally modest.
• Ciprofloxacin is identified as the antibiotic of choice due to high sensitivity rates.
• Prompt diagnosis and targeted antibiotic therapy are essential for managing this condition.