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Updated: Aug 29, 2026

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
Published on: November 21, 2025
Modified transthecal digital block versus traditional digital block for anesthesia of the finger
Alexander J Cummings1, William B Tisol, Lynne E Meyer
1Department of Surgery, University of Illinois College of Medicine at Peoria, Emergency Medicine Residency Program, OSF Saint Francis Medical Center, 530 NE Glen Oak Avenue, Peoria, IL 61637, USA.
Purpose:
This study compared the modified transthecal digital block (MTDB) technique with the traditional digital block (TDB) according to the degree of discomfort caused by injection and to the onset and the duration of anesthesia.
Methods:
This was a prospective, randomized, double-blinded, and controlled study. The same investigator performed all blocks to the middle fingers of each hand. The hand anesthetized and type of block (TDB or MTDB) received first were both randomized. An orientation was given to the 25 participants detailing how to evaluate their own degree of anesthesia. This orientation included establishing a baseline of sensation with a safety pin, a description and diagram of 12 zones of the finger, an explanation of the 10-cm visual analog pain scale, and an explanation of how to record anesthesia progress in the fingers. On completion of each block, the subjects recorded the degree of pain and time to anesthesia in each finger zone.
Results:
Twenty-five subjects received 1 TDB and 1 MTDB for a total of 50 blocks. The TDB received a mean rating for pain of 2.972 versus 2.784 for the MTDB (p =.579). The TDB took 3.91 minutes on average to take effect, whereas the MTDB took 7.16 minutes, a difference of 3.25 minutes. This was statistically significant in 11 of the 12 zones. Overall, return to sensation from the MTDB took effect 4.63 minutes sooner than the TDB: on average 85.19 minutes versus 89.82 minutes, respectively. This was statistically significant in 2 of the zones.
Conclusions:
The effect of MTDB is equal to that of TDB in terms of pain perception. For the dorsal and radial proximal zones, the TDB appears to have better distribution of anesthesia. The MTDB has slower onset to anesthesia than the TDB.
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