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Is immunotherapy effective in allergic disease?

¹St Luke's-Roosevelt Hospital Center, New York, NY 10022, USA. lfinegold@aol.com

Current Opinion in Allergy and Clinical Immunology

|January 31, 2004

Summary

Immunotherapy effectively reduces allergy symptoms and prevents new allergies. This treatment also shifts the immune system towards a non-allergic state, improving quality of life and preventing conditions like asthma.

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Area of Science:

Allergy and Immunology
Immunotherapy Research

Background:

Allergic diseases represent a significant global health burden.
Current treatments often manage symptoms without addressing underlying immune dysregulation.

Purpose of the Study:

To review the fundamental principles of effective immunotherapy.
To highlight recent advancements in immunotherapy over the past year.

Main Methods:

This is a review article, synthesizing existing research.
Focuses on published advances in immunotherapy.

Main Results:

Appropriate immunotherapy decreases allergy symptoms, medication use, and improves quality of life.
It significantly reduces the progression from allergic rhinitis to asthma and prevents new allergy development.

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Laboratory studies confirm a shift in immune function from T helper type 2 to T helper type 1 cells.

Conclusions:

Immunotherapy is a proven therapeutic intervention for allergic diseases.
Recent evidence strongly supports its efficacy as a preventive strategy against allergy development and progression.