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Updated: Aug 29, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Coronary artery bypass grafting: are risk models developed from on-pump surgery valid for off-pump surgery?
YingXing Wu1, Gary L Grunkemeier, John R Handy
1Providence Health System, Portland, OR, USA. yingxing.wu@providence.org
Objective:
This study was undertaken to test whether risk models developed from on-pump coronary artery bypass grafting are valid for assessing the risk for off-pump coronary artery bypass grafting.
Methods:
From January 1997 through June 2002, a total of 12,845 patients underwent isolated coronary artery bypass grafting procedures in Providence Health System hospitals. Of these, 1782 operations (14%) were performed without cardiopulmonary bypass. An operative mortality risk model was derived from on-pump data with logistic regression. This model and two other external risk models developed from on-pump data were then applied to patients undergoing off-pump coronary artery bypass grafting to test the model adequacy.
Results:
Good model discrimination and calibration were obtained from all three models.
Conclusion:
Operative mortality risk models developed from on-pump coronary artery bypass grafting can be used to assess the risk for off-pump coronary artery bypass grafting.
