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Published on: July 21, 2023
Imaging strategies in children with suspected appendicitis
Karen Rosendahl1, Stein Magnus Aukland, Kari Fosse
1Department of Pediatric Radiology, Haukeland University Hospital, 5021 Bergen, Norway. karen.rosendahl@helse-bergen.no
Insights
Pediatric appendicitis diagnosis benefits from imaging. Ultrasound (US) is the first choice, with computed tomography (CT) used as a supplementary tool to improve accuracy in diagnosing appendicitis in children.
Area of Science:
- Pediatric Surgery
- Diagnostic Imaging
- Emergency Medicine
Background:
- Appendicitis is a common pediatric surgical emergency, often presenting with atypical symptoms, particularly in younger children, leading to delayed diagnosis.
- Clinical assessment alone for appendicitis in children has limitations, with accuracy ranging from 70-90% and a significant rate of normal appendectomies (13-25%).
Purpose of the Study:
- To review and compare the accuracy of various imaging modalities for diagnosing acute appendicitis in children.
- To determine the optimal imaging strategy for suspected pediatric appendicitis.
Main Methods:
- Extensive literature review of studies evaluating imaging techniques for acute appendicitis in pediatric populations.
- Analysis of reported sensitivity and specificity for Ultrasound (US) and helical Computed Tomography (CT) scans.
- Inclusion of findings from a randomized study comparing US alone versus US combined with CT.
Main Results:
- Preoperative imaging significantly reduces the normal appendectomy rate to 3-7% without increasing perforation rates.
- Helical CT shows higher sensitivity (95-97%) than US (87-95%), while both have comparable specificity (US: 85-98%, CT: 94-97%).
- A combination of US and CT increased sensitivity to 99% but slightly decreased specificity to 89% compared to US alone.
Conclusions:
- Imaging is recommended for all children with suspected appendicitis.
- Ultrasound (US) should be the initial imaging modality.
- Computed Tomography (CT) serves as a valuable complementary tool when US is inconclusive or to further enhance diagnostic accuracy.
Abstract:
Appendicitis is the commonest acute surgical emergency of childhood, and occurs in approximately 2-4 per 1000 infants. It is usually seen in infants older than 5 years but can occur at any age. Atypical clinical findings are seen in 30-50% of children, especially the younger ones, and often leads to a delayed diagnosis. Preoperative clinical assessment alone has yielded an accuracy ranging between 70 and 90% but is associated with a normal appendectomy rate of 13-25%. Preoperative imaging using the graded compression US technique and/or different helical CT techniques has been able to reduce this rate to 3-7% without an increase in perforation rate. An extensive review of the literature revealed several papers examining the accuracy of different imaging modalities and strategies of acute appendicitis in children. The reported sensitivity of US varied between 87 and 95%, vs 95-97% for helical CT, while the specificity ranged between 85 and 98% for US and 94 and 97% for helical CT. Only one truly randomised study was found, showing that compared with US alone, a combination of US and helical CT increased the sensitivity from 86 to 99%, while the specificity decreased from 95 to 89%. We conclude that imaging should be performed in all children with suspected appendicitis and that US should be the initial procedure with CT as a complementary tool.
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