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Updated: Aug 29, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
[Epilepsy surgery in childhood: theory and practice]
András Fogarasi1, Magdolna Neuwirth, Zsuzsa Gyorsok
1Magyarországi Református Egyház Bethesda Gyermekkórháza, Budapest. afogarasi@bethesda.hu
Insights
For drug-resistant epilepsy in children, surgical intervention may be beneficial. Early surgery can prevent negative impacts on psychomotor development in pediatric epilepsy patients.
Area of Science:
- Pediatric Neurology
- Neurosurgery
Context:
- Epilepsy affects 1-1.5% of Hungarian children, with 20% experiencing drug-resistant seizures.
- Advancements in neuroimaging and monitoring have improved presurgical evaluation for pediatric epilepsy.
Purpose:
- To summarize key presurgical evaluation steps for pediatric epilepsy.
- To review surgical treatments for childhood epilepsy syndromes.
Summary:
- The study analyzed 58 pediatric epilepsy cases undergoing surgery.
- Common etiologies included dysplasia and benign tumors (59%).
- Surgical procedures included resection, callosotomy, and hemispherotomy.
Impact:
- Highlights the importance of early surgical intervention for therapy-resistant epilepsy in children.
- Aims to prevent adverse psychomotor development effects associated with chronic epilepsy.
Abstract:
1-1.5% of the Hungarian child population has epilepsy, and around 20% of them produces seizures in spite of modern antiepileptic drugs. A part of the pharmaco-resistant children may benefit from surgical removal of the epileptogenic focus. Presurgical evaluation has been developed a lot since the progress of neuroimaging, video-EEG monitoring, neuropsychology, and neurosurgical techniques in the 1990s. Authors summarize the important steps of presurgical evaluation in epileptic children emphasizing the role of history taking, physical examination, neuroimaging, standard EEG, long term monitoring, and neuropsychology. They describe the surgical treatment of the most important epilepsy syndromes in childhood analyzing the data of 58 epileptic children examined in the Bethesda Children's Hospital and operated in the National Institute of Neurosurgery (Budapest, Hungary). Age of children at surgery was between 16 months and 18 years, dysplasia and benign tumors covered etiology in 59% of the cases. The most frequent intervention was resection; however also some callosotomies and hemispherotomies were completed. Authors emphasize the importance of early surgical intervention of therapy resistant children in order to prevent the deteriorating effects of epilepsy on childhood psychomotor development.
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