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Thiazolo[3,2-a]pyrimidine derivatives as calcium antagonists
1Department of Pharmaceutical Chemistry, Hacettepe University, Faculty of Pharmacy.
Die Pharmazie
|September 1, 1992
Abstract:
Some new thiazolo[3,2-a]pyrimidine derivatives were prepared refluxing 2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives with phenacyl bromide in glacial acetic acid. Calcium antagonistic activities of these compounds were evaluated in K(+)-depolarized rat aorta, using nifedipine as reference compound.