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Updated: Aug 14, 2026
Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
[Effects of repeated body position change training for human orthostatic tolerance]
Bin Wu1, Guang-xing You, Ping Wu
1Institute of Space Medico-Engineering, Beijing, China.
Objective:
To verify the validity that repeated position change training can increase human orthostatic tolerance and to explore its mechanism.
Method:
Six subjects were trained with repeated position change for 11 d according to a protocol of alternative head-down and head-up tilts, each set of training lasted for about 35 min. Their orthostatic tolerances were determined before and after training.
Result:
Compared with the data before training, subjects' symptom scores during orthostatic tolerance test after training decreased significantly (4.50 +/- 1.05 vs. 2.83 +/- 1.60, P<0.05), magnitude of the increased heart rate increase lowered significantly [(29.3 +/- 4.3) bpm vs. (13.5 +/- 7.5) bpm, P<0.01], magnitude of mean arterial blood pressure augmentation increased significantly [(4.8 +/- 4.4) mmHg vs. (9.0 +/- 3.0) mmHg, P<0.05] and cardiovascular response index decreased significantly (34.42 +/- 5.00 vs. 22.33 +/- 8.27, P<0.01). In brief, the responses to orthostatic stress were improved after training.
Conclusion:
Repeated alternative body position change training can increase human orthostatic tolerance. This kind of training is promising for pilot, especially astronaut training.
