Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Relation between brain oxygen metabolism and temperature gradient between brain and bladder.

A Sakurai1, K Kinoshita, T Atsumi

  • 1Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan. sakurai@med.nihon-u.ac.jp

Acta Neurochirurgica. Supplement
|February 3, 2004
PubMed
Summary

Brain temperature fluctuations after severe brain injury indicate potential brain ischemia. A higher temperature gradient correlated with lower jugular venous oxygen saturation, suggesting impaired brain perfusion.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chimera Time-Crystalline Order in Quantum Spin Networks.

Physical review letters·2021
Same author

A clinical investigation of the association between perioperative oral management and prognostic nutritional index in patients with digestive and urinary cancers.

Current oncology (Toronto, Ont.)·2020
Same author

Whole-genome sequencing of Staphylococcus epidermidis bloodstream isolates from a prospective clinical trial reveals that complicated bacteraemia is caused by a limited number of closely related sequence types.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2019
Same author

Effects of 3-Methylgibberellin Analogs on Gibberellin 3β-Hydroxylases and Plant Growth.

Bioscience, biotechnology, and biochemistry·2016
Same author

Effect of Uniconazole and Gibberellin on the Flowering of Pharbitis nil.

Bioscience, biotechnology, and biochemistry·2016
Same author

[Delayed augmentation effect of cytokine production after hyperthermia stimuli].

Molekuliarnaia biologiia·2015

Area of Science:

  • Neuroscience
  • Critical Care Medicine
  • Physiology

Background:

  • Brain temperature typically exceeds systemic core temperature.
  • Recent studies noted fluctuations in the brain-core temperature gradient after severe brain insults.
  • The clinical significance of these temperature gradient changes remains unclear.

Purpose of the Study:

  • To investigate the fluctuations of the temperature gradient between brain and core body temperatures following severe brain injury.
  • To determine the relationship between temperature gradient, cerebral perfusion pressure (CPP), and jugular venous oxygen saturation (SjO2) in brain-injured patients.

Main Methods:

  • Measured temperature gradient (brain minus bladder temperature) in 11 severe brain injury patients (subarachnoid hemorrhage, cerebral hemorrhage, traumatic brain injury).

Related Experiment Videos

  • Simultaneously recorded cerebral perfusion pressure (CPP) and jugular venous oxygen saturation (SjO2).
  • Analyzed data from 125 measurement points.

    • Main Results:

    • The average temperature gradient was 0.29 ± 0.285°C when CPP was >50 mmHg.
    • A significant inverse correlation was found between SjO2 and the temperature gradient (r = 0.472; P < 0.0001) at CPP >50 mmHg.
    • Temperature gradients showed a tendency to increase and then decrease when CPP <50 mmHg.

    Conclusions:

    • Increased temperature gradient is significantly inversely correlated with SjO2 in severe brain injury patients with CPP >50 mmHg.
    • Fluctuations in the brain-core temperature gradient may serve as an indicator of brain ischemia in critical conditions.
    • Monitoring the temperature gradient could offer insights into brain perfusion status.