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[Neuronal migration anomalies. The magnetic resonance aspects of some types]
The authors investigated the value of magnetic resonance (MR) imaging in the evaluation of some types of neuronal migration anomaly. During pregnancy, a radial neuronal migration from germinal matrix to cortex occurs in the fetal brain, and 6 layers are formed. Infections, traumas, vascular factors can block the migration. Neuronal migration disorders are divided into 5 different classes: (1) agyria-pachigyria complex; (2) schizencephaly; (3) polymicrogyria; (4) unilateral megaencephaly; (5) heterotopia. In this study, 12 patients were evaluated with MR imaging: 5 had lissencephaly, 4 heterotopia and 3 schizencephaly (2 with open lips, and 1 with closed lips). MR imaging is the method of choice in these patients; indeed, characteristic morphologic and signal patterns allow the correct evaluation and diagnosis of neuronal migration anomalies in all cases.
The authors investigated the value of magnetic resonance (MR) imaging in the evaluation of some types of neuronal migration anomaly. During pregnancy, a radial neuronal migration from germinal matrix to cortex occurs in the fetal brain, and 6 layers are formed. Infections, traumas, vascular factors can block the migration. Neuronal migration disorders are divided into 5 different classes: (1) agyria-pachigyria complex; (2) schizencephaly; (3) polymicrogyria; (4) unilateral megaencephaly; (5) heterotopia. In this study, 12 patients were evaluated with MR imaging: 5 had lissencephaly, 4 heterotopia and 3 schizencephaly (2 with open lips, and 1 with closed lips). MR imaging is the method of choice in these patients; indeed, characteristic morphologic and signal patterns allow the correct evaluation and diagnosis of neuronal migration anomalies in all cases.