Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Smallpox: clinical features, prevention, and management.

Roy Guharoy1, Robert Panzik, John A Noviasky

  • 1Section of Clinical Pharmacology, SUNY-Upstate Medical University, Syracuse, NY, USA. GuharoyR@Upstate.edu

The Annals of Pharmacotherapy
|February 3, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A call to action for adverse drug event (ADE) detection and prevention.

Frontiers in digital health·2025
Same author

Factors Associated with Acute Injurious Falls in Elderly Hospitalized Patients: A Multicenter Descriptive Study.

Joint Commission journal on quality and patient safety·2023
Same author

Creating Data Standards to Support the Electronic Transmission of Compounded Nonsterile Preparations (CNSPs): Perspectives of a United States Pharmacopeia Expert Panel.

Children (Basel, Switzerland)·2022
Same author

Longitudinal Evaluation of a Deprescribing Protocol in Skilled Nursing Facilities.

The Senior care pharmacist·2022
Same author

Efficacy and Safety of Megestrol in the Hospitalized Older Person.

The Senior care pharmacist·2022
Same author

Impact of a Clinical Pharmacist Telehealth Service in a Geriatrics Assessment Clinic.

The Senior care pharmacist·2022

Smallpox, though eradicated, poses a bioterrorism risk. Understanding smallpox vaccine adverse events and contraindications is crucial for healthcare professionals managing vaccination programs.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Vaccinology

Background:

  • Smallpox, a contagious disease with a 30% mortality rate, was eradicated globally by 1980.
  • Concerns exist regarding smallpox as a potential bioterrorism agent.
  • Current vaccination programs in military and civilian sectors necessitate awareness of vaccine risks.

Purpose of the Study:

  • To provide a comprehensive overview of smallpox.
  • To detail clinical presentation, diagnosis, and management strategies.
  • To describe adverse events and contraindications associated with smallpox vaccination.

Main Methods:

  • Literature review of MEDLINE and International Pharmaceutical Abstracts (1966-2003).
  • Search terms included smallpox, bioterrorism, biological warfare, and smallpox vaccine.

Related Experiment Videos

  • Relevant articles were evaluated for inclusion in the review.

    • Main Results:

    • Smallpox is highly contagious through human-to-human contact.
    • Smallpox vaccine can cause moderate to severe adverse events, including eczema vaccinatum, progressive vaccinia, and generalized vaccinia.
    • The risk-benefit analysis of mass smallpox vaccination remains unclear.

    Conclusions:

    • Healthcare professionals must understand smallpox vaccine adverse events and contraindications.
    • The Centers for Disease Control and Prevention (CDC) has issued guidelines for civilian smallpox vaccine use.
    • The equipoise between vaccination risks and epidemic prevention benefits requires further evaluation.