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Updated: Aug 29, 2026

Generating Transgenics and Knockouts in Strongyloides Species by Microinjection
Published on: October 7, 2021
[Strongyloides stercoralis in the south of Galicia]
C Martínez-Vázquez1, G González Mediero, M Núñez
1Sección de Microbiología y Parasitología, Hospital Xeral-Cíes, Unidad de Enfermedades Infecciosas, Universidad de Santiago, Vigo.
Abstract:
Strongyloides stercoralis is the only parasite which can produce a chronic illness in humans, being through autoinfection. This nematode can also provoke death when patient's immunologic state deteriorates producing a massive hyper infection. The first patient with strongyloidiasis who has always lived in the Galician South area is described. The clinical picture consisted of unspecific cutaneous lesions and abdominal pain with severe peripheral eosinophilia (> 20,000/ml. The diagnosis was carried out observing the larvae in the fecal examination and was confirmed with a culture. Treatment with albendazole failed and the healing was reached with ivermectin. We must consider the possibility of strongyloidiasis because misdiagnosing these patients as eosinophilic gastroenteritis there would be a higher risk of hyperinfection if they are treated with corticosteroids.
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